[Effective tocolysis without ß-agonists].

UNLABELLED: Many years the ß-mimetics (Partussisten, Gynipral) were first line tocolytic agents in terms of delaying premature delivery in our country. As these medicaments have been withdrawn from the pharmacy network, some concerns began to appear among our colleges considering the administration of other tocolytics and their effectiveness. Our goal is to compare the efficacy of other tocolytics with ß-mimetics. That is why we reviewed the structure of premature deliveries in the University Hospital "Stoyan Kirkovich", Stara Zagora for two periods: 01.01.2013 - 31.12. 2013 and 01.01.2014 - 01.06.2014. RESULTS: 45 of 326 pregnancies (13.8%) > 20 weeks of gestation for 2013, treated with Gynipral have ended with a premature delivery vs. 13 of 110 pregnancies (11.8%), treated with magnesium (Mg SO4, Magnerich, Magnerot), calcium channel blockers and spasmolyticsfor the period - 01:01.2014 - 01.06.2014. CONCLUSION: The results show, that at this stage, several months after the cessation of use of ß-mimetics, there is no rise of number and percentage of premature deliveries, but there is even a tendence of decline. Larger periods and greater number of cases are needed to formulate conclusions with greater significance.

[Tumor size and prognosis for patients with epithelial ovarian carcinoma at early stage].

UNLABELLED: The goal of the research is to discover and analyze the dependence of survival on the tumor size in a cohort of 215 female patients with early epithelial ovarian cancer fallowed up for 13 year period (2000-2012). After multiple analyze among 18 other prognostic factors, using Cox proportional regression, tumor size remained one of five most significant. CONCLUSION: The bigger the size of the tumor, the poorer the prognosis for the overall survival (p = 0.0001) and progression free survival (p = 0.4) of patient with epithelial ovarian cancer at early stage.

[Laparoscopy and early ovarian cancer].

UNLABELLED: Review of modern opinions and tendencies, concerning the role of laparoscopic surgery for the staging and treatment of ovarian cancer stage I-II. CONCLUSION: The laparoscopic approach of surgical staging of early ovarian cancer is equal and even has more advantages then conventional laparotomy if it is performed from gynecologists- oncologists with enough skills and experience in laparoscopic surgery.

[Operative treatment--prognostic factor in patients with ovarian cancer stage I-II].

OBJECTIVE: The authors present and analyze the modern concepts of the role of surgery as a prognostic factor for patients with early epithelial ovarian cancer (st. I-II). They review, synthetize and summarize the information from 15 studies, published in the recent years, and concerning the subject. CONCLUSION: Surgery treatment for early epithelial ovarian cancer is one of the most important prognostic factors. The appropriate surgical performance contributes either for complete staging or for optimal primary cytoreduction and strongly influence the development and outcome of disease.

[The role of adjuvant chemotherapy as a prognostic factor in patients with early stage of epithelian ovarian cancer (I - II stage)].

UNLABELLED: The authors present and analyze the modem concepts of the role of adjuvant chemotherapy as a prognostic factor for patients with early epithelial ovarian cancer (st. I-II). They review, synthetize and summarize the information from studies and researches, published in the recent years, and concerning the subject. CONCLUSION: Adjuvant chemotherapy for early epithelial ovarian cancer improves overall survival of patients having tumors with grade 2 or 3, stagelC or grater and suboptimal surgical staging.

[Impact of the ammount of medicaments, administered as adjuvant chemotherapy, over the survival of female patients with early epitelial ovarian cancer].

UNLABELLED: A cohort of 215 female patients with early epithelial ovarian cancer, researched for 13 year period (2000-2012). The authors are setting a goal to investigate how does the amount of chemotherapeutic medicaments, administered as adjuvant therapy influences the survival of these patients. CONCLUSION: The application of three or more chemotherapeutic agents does not improve the survival of female patients with early epithelial ovarian cancer, indicated for chemotherapy.

[Postoperatively conformed effectiveness of preoperative radio therapy, combined with chemotherapy - cysplatin].

The authors present a case of a 35 years old female patient with spinocellular carcinoma of the cervix, diagnosed after byopsy and treated with radiotherapy 30 Gray, combined with Cisplatin 50 mg. per square meter, per week, 6 months before radical histerectomy and lymphonodulectomy was performed. The postoperative histology shows only traces of dysplastic epithelia, which proves preoperative therapy effective.

[Endometrial cancer, turned out to be an endometroid ovarian cancer stage II].

43 years old female patients endometrial biopsy diagnosis shows highly differentiated adenocarcinoma. Because of this result she underwent total hysterectomy two weeks later, and the new hystology result is: highly differentiated endometroid ovarian carcinoma.

[Female with severe multiorgan damage and algetic myoma utery].

Painfull myoma utery in a patient with poor health condition and many disfunctional organs: Diabetes mellitus, Chronic renal insufficiency Gr. III (most probably a result of compression of the ureters causing bilateral hydronephrosis), arterial hypertony, anemia. The authors introduce their therapeutic model and manage to perform successfull operation after stabilizing the patient and intensive postoperative care. They point out the team work and good synchronization between the hospital divisions as crucial for the success of the treatment.

[Angioleiomyoma utery in a female patient with damaged health condition. Diagnostic and terapeutic difficulties].

35 years old patient with many health problems, on a haemodialysis and a big abdominal tumor originating from the pelvis. The authors share their clinical approach and their diagnostic and terapeutic difficulties in this case and refer to one of their previous publications.

[Rare form of cervix carcinoma, infiltrating cervical myoma].

The authors describe rare case of carcinoma colli uteri, which grows to infiltrate submucose cervical myoma.

[Operative method of cervix conisation].

The authors describe an operative method of cervix conisation, which they used by 41 patients in a 11-years period (1998-2009). Shearing their experience of the results they achieved, they are making some conclusions.

[Fetal mortality of children in breech presentation for the period 1990-2001 (12 years)].

The authors review 12-years period (1990-2001) during which they research the fetal mortality of children born in breech presentation in the University clinic of Obstetrics and Gynecology of Stara Zagora, Bulgaria. They present a figure of the possible risks for the fetus in breech presentation and breech delivery.

[Rate of cesarean section with breech presentation in Stara Zagora for 12-years period].

The authors review and analyse the structure and the rate of the cesarean section with breech presentation in Stara Zagora, Bulgaria, for 12-years period. They present their algorithm of work.

[Multiple pregnancy and breech presentation].

The article is about multiple pregnancy with twins during labor, when the first twin is in vertex presentation and the second is in breech presentation. The authors observe the obstetrical management in this combination in the clinic of Obstetrics and Gynecology in Stara Zagora for 12 years period--1990-2001.

[Choice of the type of manual assistance used during delivery of a fetus in breech presentation].

The authors show statistics of the manual assistance methods, performed by the obstetricians in the clinic of obstetrics and gynecology of Stara Zagora, when delivering of fetuses in breach presentation. They observe 12-year period and introduce their algorithm.

[Prematurity, breech presentation, and delivery].

The authors research 248 immature infants (> 1000 < 2500 g), born in breech presentation in the Clinic of Obstetrics and Gynecology, Stara Zagora in 12 years (1990-2001).

[Roberts syndrome. Case report and literature review].

Mature infant born with tetraphocomelia from 26 years old mother after uncomplicated unobserved pregnancy. Rare case of Roberts Syndrome.

[Giant uterus myoma in patient of 84 years old. Case report and discussion].

The authors of the present report describe a case of myoma utery permagna developped in 84-years old female, who hasn't recieved HRT. Despite being a rare finding at this age, the giant myoma pennit us to rise a question about the hormonal influence of the etrogens on the growth of this tumor.

[Laparoscopic cholecystectomy during pregnancy. Case report and literature review].

The outors report of two cases of sucsessfully done laparoscopic cholecystectomy in pregnant women with cholelithiasis. The first patient was pregnant with 6 lunar months and suffering of acute cholecystitis, and the second woman is pregnant in 4-th lunar month whith cholelithiasis. During both postoperative periods--no complications. The pregnancies in both cases ended in therm and healthy mature children was born. We make a brief literature review and present whith the opinion that with strong indications and good prepared and experienced surgents, laparoscopic cholecystectomy is a method of choice.